Polyhexanide is odorless, colorless and hypoallergenic, does not burn in the wound and, according to current literature and does not cause wound healing disorders. Polyhexanide damages and kills bacteria in very low concentrations by binding to the cell wall of bacteria. Polyhexanide is applicable as a gel or solution in diluted form on the skin. Misapplications in Apomorphine therapy may cause drug leakage from the needle site c and may form superficial necrosis. Necrosis is understood in biology and medicine as death of single or multiple cells. A necrosis is a pathological process and is triggered by harmful effects on the cell. In consultation with the doctor, Polyhexanide may be used to relieve necrosis.